Metabolism of antipsychotic drugs in asians
I was reading the NICE guidelines on "Consensus statement on high-dose antipsychotic medication", latest (2014) version. In the section on 'Potential gender and ethnicity factors and high-dose strategies' it says: Genetic polymorphisms at both the metabolic level and site of action are likely to contribute to the overall response to a particular drug. Some Asian patients might have a lower dose threshold for a variety of Extrapyramidal side-effects.